Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a-/- mice

Figure 3 Administration of a Prunella vulgaris ethanolic extract reduced local myeloperoxidase activity in the colon of mdr1a^-/- mice. Homogenates of colonic tissue were subjected to an assay for MPO activity. ^aP < 0.05, ^bP < 0.01 compared to mdr1a^-/- vehicle as calculated by Kruskal-Wallis test. Vehicle-treated FVB^WT mice n = 6, vehicle-treated mdr1a^-/- mice n = 10, P. vulgaris-treated mdr1a^-/- mice n = 7. MPO: Myeloperoxidase; P. vulgaris: Prunella vulgaris.