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©The Author(s) 2015.
World J Gastrointest Pharmacol Ther. Nov 6, 2015; 6(4): 183-198
Published online Nov 6, 2015. doi: 10.4292/wjgpt.v6.i4.183
Published online Nov 6, 2015. doi: 10.4292/wjgpt.v6.i4.183
Table 1 Decline in rates of Helicobacter pylori eradication following first-line standard triple therapy
Country | Ref. | Publication | Treatment duration | Patients | Therapy regimen | Eradication rate (ITT) | Eradication rate (PP) |
South Korea | Na et al[177] | 2007 | 7 d | 3267 | Standard PPI | NA | 84.3% |
Cla 500 mg bid | |||||||
Amo 1 g bid | |||||||
Chung et al[178] | 2012 | 10 d | 80 | Lan 30 mg bid | 58.7% | 67.6% | |
Cla 500 mg bid | |||||||
Amo 1 g bid | |||||||
Japan | Asaka et al[179] | 2001 | 7 d | 96 | Lan 30 mg bid | NA | 90.7% |
Cla 200 mg bid | |||||||
Amo 750 mg bid | |||||||
Fujioka et al[180] | 2012 | 7 d | 3162 | Rab 10 mg bid | 80.7% | NA | |
Amo 750 mg bid | |||||||
Cla 200 mg bid | |||||||
Nishizawa et al[27] | 2012 | 7 d | 55 | Lan 30 mg bid | 74.5% | 80.4% | |
Cla 400 mg bid | |||||||
Amo 750 mg bid | |||||||
Nishida et al[181] | 2014 | 7 d | 134/134 | Eso 20 mg bid | 69.4%/73.9% | 76.9%/79.8% | |
Cla 400 mg bid | |||||||
Amo 750 mg bid | |||||||
Lan 30 mg bid | |||||||
Cla 400 mg bid | |||||||
Amo 750 mg bid | |||||||
Taiwan | Sheu et al[182] | 2000 | 7 d or 2 wk | 286 | Ome 20 mg bid | NA | 87.8% |
Amo 1 g bid | |||||||
Cla or Met bid | |||||||
Chen et al[117] | 2014 | 7 d | 73 | Rab 20 mg bid | 57.5% | 61.8% | |
Cla 500 mg bid | |||||||
Amo 1 g bid | |||||||
Turkey | Ozçay et al[183] | 2004 | 4 wk: PPI 2 wk:Cla, Amo | 102 | Ome or Lan | NA | 75.7% |
Cla 7.5 mg/kg bid | |||||||
Amo 20 mg/kg bid | |||||||
Kutluk et al[184] | 2014 | 10 d | 74 | Lan 1 mg/kg per day | 52.7% | 55.7% | |
Cla 20 mg/kg per day | |||||||
Amo 50 mg/kg per day | |||||||
Italy | Catalano et al[185] | 1999 | 10 d | 84 | Ome 20 mg bid | NA | 94.0% |
Cla 500 mg bid | |||||||
Amo 1 g bid | |||||||
Paoluzi et al[186] | 2010 | 7 d | 90 | Eso 20 mg bid | 66.0% | 75.0% | |
Cla 500 mg bid | |||||||
Amo 1 g bid | |||||||
Latin America | Greenberg et al[106] | 2011 | 14 d | 488 | Lan 30 mg bid | 82.2% | 87.1% |
Cla 500 mg bid | |||||||
Amo 1 g bid |
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Citation: Kim SY, Choi DJ, Chung JW. Antibiotic treatment for
Helicobacter pylori : Is the end coming? World J Gastrointest Pharmacol Ther 2015; 6(4): 183-198 - URL: https://www.wjgnet.com/2150-5349/full/v6/i4/183.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v6.i4.183