Review
Copyright ©The Author(s) 2015.
World J Gastrointest Pharmacol Ther. Aug 6, 2015; 6(3): 59-72
Published online Aug 6, 2015. doi: 10.4292/wjgpt.v6.i3.59
Table 1 Different antioxidants found in food (clinical effects and relevance)
AntioxidantMain clinical effectsClinical relevance
CurcuminAntioxidantNo studies available in human hepatic disorders
Anti-fibrotic
Anti-inflammatory
Anti-microbial
Wound healing
Anti-carcinogenic
ResveratrolAntioxidantCurrent data are contradictory, more clinical studies are needed
Anti-inflammatory
Anti-carcinogenic
Lipid modulation
Antifibrotic
CoffeeAntinecroticInverse relationship between coffee-cirrhosis has been demonstrated, but it is
Antifibroticnecessary to do more basic research and prospective clinical trials
Antioxidant
Anticholestatic
Chemoprotective
QuercetinChelation of transition metal ionsNo studies available in human hepatic disorders
Anti-carcinogenic
Cardioprotective
Bacteriostatic
Antioxidant
Antifibrotic
Anti-inflammatory
Anti-apoptotic
Anti-aggregatory
Vasodilating
SilymarinAntioxidantSilymarin has been shown to be effective, but it is necessary to do more clinical
Antifibrotictrials focused on survival rates of patients with cirrhosis
Anti-inflammatory
Anti-carcinogenic
Immunomodulation
NaringeninAntioxidantNo studies available in human hepatic disorders
Hypocholesterolemic
Anti-estrogenic
Hypolipidemic
Antihypertensive
Anti-inflammatory
Antifibrotic
Anti-carcinogenic
Anti-atherogenic
Green teaAnti-inflammatory
Anti-arthriticMore clinical studies are needed
Antimicrobial
Antioxidant
Neuroprotective
Antidiabetic
Antiangiogenesis
Anti-carcinogenic