Protein kinases are potential targets to treat inflammatory bowel disease

Figure 2 Intestinal Goblet cells employ different mechanisms including protein kinase related pathways to modulate the secretion of mucus, such as pathways related to tyrosine kinase, protein kinase C delta, myristoylated alanine-rich C-kinase substrate or receptors with tyrosine kinase activity such as epidermal growth factor receptor. MARCKS: Myristoylated alanine-rich C-kinase substrate; EGFR: Epidermal growth factor receptor; TK: tyrosine kinase; RELM-beta: Resistin-like molecule beta; PKCδ: Protein kinase C delta; MAPK: Mitogen activated protein kinase.