Ischemic heart disease, factor predisposing to Barrett’s adenocarcinoma: A case control study

Table 4 Main demographic and disease related characteristics and treatment received in patients with ischemic heart disease and Barrett esophagus or esophageal adenocarcinoma n (%)

Characteristic	BE n = 83	AdE n = 40	P
Age [mean (SD)], yr	75 (SD = 10)	78 (SD = 10)	0.12
Male gender	54 (65)	23 (58)	0.54
Active smokers	23 (28)	10 (25)	0.92
Alcohol abusers	18 (22)	8 (20)	0.98
Cig. Cons. (in PY) [mean (SD)]	43 (SD = 25)	33 (SD = 17)	0.02
Low socioeconomic status	21 (25)	12 (30)	0.74
Diabetes	16 (19)	1 (3)	0.02
Barrett’s length (in cm)	6.4 (SD = 3.6)	7.1 (SD = 4.4)	0.35
Presence of hiatal hernia	55 (66)	27 (68)	0.95
Hyperlipidemia under treatment	77 (93)	36 (90)	0.86
Hypertension	58 (70)	30 (75)	0.71
Dur ref (in years) [mean (SD)]	19 (SD = 10)	28 (SD = 10)	< 0.0001
Freq ref (d/wk): [mean (SD)]	5.3 (SD = 2.3)	6 (SD = 2)	0.1
BMI ≥ 25	45 (54)	19 (48)	0.61
Use of beta-blockers	79 (95)	37 (93)	0.85
Sphincter relaxing medication	62 (75)	19 (47)	0.005
Low dose aspirin	42 (51)	12 (30)	0.03
Low dose aspirin daily	39 (47)	8 (20)	0.004

Cig. Cons.: Cigarette consumption in total throughout life; PY: Pack years; BMI: Body mass index; Dur ref: Duration of reflux; Freq ref (d/wk): Frequency of reflux episodes; BE: Barrett esophagus; AdE: Esophageal adenocarcinoma.