Ischemic heart disease, factor predisposing to Barrett’s adenocarcinoma: A case control study

Table 2 Comparison of the main demographic endoscopic and clinical characteristics between patients with Barrett’s esophagus and esophageal adenocarcinoma n (%)

Characteristics	Barrett’s esophagus (n = 426)	Esophageal adenocarcinoma (n = 120)	P
Age [mean (SD)], yr	68 (SD = 14)	73 (SD = 11)	0.0003
Male gender	264 (61)	73 (61)	0.82
Smokers	136 (32)	44 (37)	0.39
Cig. Cons. (in PY) [mean (SD)]	19.8 (SD = 28.4)	22.5 (SD = 30.2)	0.36
Alcohol abusers	108 (25)	32 (27)	0.86
Barrett’s length (in cm)	6.6 (SD = 3.9)	7.5 (SD = 4.2)	0.03
Presence of hiatus hernia	304 (71)1	73 (61)	0.04
BMI ≥ 25	232 (54)	57 (48)	0.21
Low socioeconomic status	69 (16)	26 (22)	0.21
Dur of reflux (in Y) [mean (SD)]	16.1 (SD = 9.9)	28.5 (SD = 10.1)	< 0.0001
Freq of reflux (d/wk) [mean (SD)]	5.1 (SD = 2.3)	5.4 (SD = 2.4)	0.21

¹Thirty/fifty (60%) of patients with short segment Barrett present a hiatus hernia, as well as 5/10 (50%) with AdE on short segment Barrett esophagus. Y: Years; Cig. Cons.: Cigarette consumption in total throughout life; PY: Pack-years; BMI: Body mass index; Dur of reflux: Duration of reflux; Freq of reflux (d/wk): Frequency of reflux episodes in days/week.