Association of ITPA polymorphism with outcomes of peginterferon-&alpha; plus ribavirin combination therapy

doi:10.4292/wjgpt.v4.i3.54

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. Aug 6, 2013; 4(3): 54-60
Published online Aug 6, 2013. doi: 10.4292/wjgpt.v4.i3.54

Table 5 Multivariate analysis for predictive factors associated with SVR

Factors	Category	95%CI	P value
HCV RNA (log IU/mL)	≥ 6.0: 1.0	1.42-10.95	0.008
	< 6.0: 3.94
IL28B (rs8099917)	TG + GG: 1.0	1.18-10.10	0.023
	TT: 3.46

HCV: Hepatitis C virus; IL28B: Interleukin 28B; SVR: Sustained virological response.

Citation: Fujino T, Aoyagi Y, Takahashi M, Yada R, Yamamoto N, Ohishi Y, Nishiura A, Kohjima M, Yoshimoto T, Fukuizumi K, Nakashima M, Kato M, Kotoh K, Nakamuta M, Enjoji M. Association of ITPA polymorphism with outcomes of peginterferon-α plus ribavirin combination therapy. World J Gastrointest Pharmacol Ther 2013; 4(3): 54-60
URL: https://www.wjgnet.com/2150-5349/full/v4/i3/54.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v4.i3.54