Comprehensive review of Clostridium difficile infection: Epidemiology, diagnosis, prevention, and treatment

doi:10.4292/wjgpt.v16.i1.100560

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Mar 5, 2025 (publication date) through Mar 3, 2025

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. Mar 5, 2025; 16(1): 100560
Published online Mar 5, 2025. doi: 10.4292/wjgpt.v16.i1.100560

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Figure 1 The molecular mechanism of the Clostridium difficile infection. CDI: Clostridium difficile infection; Tcd A: Toxin A; Tcd B: Toxin B; LDLR: Low-density lipoprotein receptor; sGAGs: Sulfated glycosaminoglycans; CSPG4: Chondroitin sulfate proteoglycan 4; TFPI: Tissue factor pathway inhibit; Rho: Ras homologous; GTPase: Guanosine triphosphate hydrolase; GTD: Glucosyltransferase domain (Created in BioRender, Supplementary material).

Citation: Wang X, Wang WY, Yu XL, Chen JW, Yang JS, Wang MK. Comprehensive review of Clostridium difficile infection: Epidemiology, diagnosis, prevention, and treatment. World J Gastrointest Pharmacol Ther 2025; 16(1): 100560
URL: https://www.wjgnet.com/2150-5349/full/v16/i1/100560.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v16.i1.100560