Predicting full-thickness necrosis in adult acute corrosive ingestion injuries in a sub-Saharan African setting

Table 7 Admission endoscopy, computed tomography and blood gas performance in predicting full thickness necrosis

	Total	FT necrosis	Not FT necrosis	Sensitivity, %	Specificity, %	PPV, %	NPV, %	P value	ROC AUC
Endoscopy performance (n = 95)
Zargar IIIB	16	12	4	75.0	94.9	75.0	94.5	< 0.001	0.850
CT performance (n = 17)
CT grade 3	5	4	1	66.7	90.9	80.0	83.3	0.026	0.788
Blood gas performance (n = 40)
pH < 7.35	20	7	13	77.8	58.1	35.0	90.0	0.062	0.679
BE < -2 mEq/L	18	7	11	77.8	64.5	38.9	90.9	0.027	0.711
Lactate > 2.0 mmol/L	21	8	13	88.9	58.1	38.1	94.7	0.014	0.735
Blood gas performance (Patients with concomitant toxin ingestion removed) (n = 35)
pH < 7.35	19	7	12	77.8	58.1	35.0	100.0	0.007	0.786
BE < -2 mEq/L	17	7	10	77.8	58.1	35.0	100.0	0.003	0.821
Lactate > 2.0 mmol/L	18	6	12	77.8	58.1	35.0	94.1	0.046	0.714

FT necrosis: Full thickness necrosis; PPV: Positive predictive value; NPV: Negative predictive value; ROC AUC: Receiver operator characteristic area under the curve; CT: Computed tomography.