Efficacy and tolerability of chitin-glucan combined with simethicone (GASTRAP® DIRECT) in irritable bowel syndrome: A prospective, open-label, multicenter study

doi:10.4292/wjgpt.v15.i3.90757

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May 28, 2024 (publication date) through Dec 28, 2024

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. May 28, 2024; 15(3): 90757
Published online May 28, 2024. doi: 10.4292/wjgpt.v15.i3.90757

Table 5 Relief of altered stool pattern at weeks 2 and 4 of GASTRAP^® DIRECT treatment

Symptom relief (% vs W0)	W2 (%)	W4 (%)
Constipation
Unchanged	58	54
Relief (very much, considerable)	42 (27, 15)	46 (37, 9)
Diarrhea
Unchanged	44	42
Relief (very much, considerable)	46 (42, 14)	58 (39, 19)
Defecatory disorders
Unchanged	56	58
Relief (very much, considerable)	44 (36, 8)	42 (31, 11)

W: Week.

Citation: Talbodec N, Le Roy P, Fournier P, Lesage B, Lepoutre E, Castex F, Godchaux JM, Vandeville L, Bismuth B, Lesage X, Bayart P, Genin M, Rousseaux C, Maquet V, Modica S, Desreumaux P, Valibouze C. Efficacy and tolerability of chitin-glucan combined with simethicone (GASTRAP^® DIRECT) in irritable bowel syndrome: A prospective, open-label, multicenter study. World J Gastrointest Pharmacol Ther 2024; 15(3): 90757
URL: https://www.wjgnet.com/2150-5349/full/v15/i3/90757.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v15.i3.90757