Prospective Study
Copyright ©The Author(s) 2024.
World J Gastrointest Pharmacol Ther. May 28, 2024; 15(3): 90757
Published online May 28, 2024. doi: 10.4292/wjgpt.v15.i3.90757
Table 4 Symptom relief at week 4 of GASTRAP® DIRECT treatment in patients with IBS having prevalent constipation, diarrhea, and mixed irritable bowel syndrome
Symptom relief at W4
IBS-C (%)
IBS-D (%)
IBS-M (%)
Abdominal pain
    Unchanged422734
    Relief (very much, considerable)58 (50, 8)73 (46, 27)66 (48, 18)
Bloating
    Unchanged423231
    Relief (very much, considerable)58 (46, 12)68 (41, 27)69 (53, 16)
Abdominal distension
    Unchanged465039
    Relief (very much, considerable)54 (39, 15)50 (36, 14)61 (39, 21)

  • Citation: Talbodec N, Le Roy P, Fournier P, Lesage B, Lepoutre E, Castex F, Godchaux JM, Vandeville L, Bismuth B, Lesage X, Bayart P, Genin M, Rousseaux C, Maquet V, Modica S, Desreumaux P, Valibouze C. Efficacy and tolerability of chitin-glucan combined with simethicone (GASTRAP® DIRECT) in irritable bowel syndrome: A prospective, open-label, multicenter study. World J Gastrointest Pharmacol Ther 2024; 15(3): 90757
  • URL: https://www.wjgnet.com/2150-5349/full/v15/i3/90757.htm
  • DOI: https://dx.doi.org/10.4292/wjgpt.v15.i3.90757