Efficacy and tolerability of chitin-glucan combined with simethicone (GASTRAP® DIRECT) in irritable bowel syndrome: A prospective, open-label, multicenter study

doi:10.4292/wjgpt.v15.i3.90757

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May 28, 2024 (publication date) through Jul 17, 2024

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. May 28, 2024; 15(3): 90757
Published online May 28, 2024. doi: 10.4292/wjgpt.v15.i3.90757

Table 1 Baseline patient characteristics, n (%)

	V1 (n = 100)
Female sex	76 (76)
Age (yr), mean ± SD	47 ± 13
IBS type
Constipation-predominant	37/98 (38)
Diarrhea-predominant	31/98 (32)
Mixed	20/98 (20)
Undefined	10/98 (10)
Stool consistency (BSS score), mean ± SD	4.1 ± 1.1
Hard stool (1–2)	14/93 (15)
Normal stool (3–5)	62/93 (67)
Liquid stool (6–7)	17/93 (18)
Excessive flatulence	91/98 (93)
Defecatory disorders	26/100 (26)

V: Visit; BSS: British stool scale.

Citation: Talbodec N, Le Roy P, Fournier P, Lesage B, Lepoutre E, Castex F, Godchaux JM, Vandeville L, Bismuth B, Lesage X, Bayart P, Genin M, Rousseaux C, Maquet V, Modica S, Desreumaux P, Valibouze C. Efficacy and tolerability of chitin-glucan combined with simethicone (GASTRAP^® DIRECT) in irritable bowel syndrome: A prospective, open-label, multicenter study. World J Gastrointest Pharmacol Ther 2024; 15(3): 90757
URL: https://www.wjgnet.com/2150-5349/full/v15/i3/90757.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v15.i3.90757