Treatment endpoints in ulcerative colitis: Does one size fit all?

doi:10.4292/wjgpt.v15.i2.91591

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May 5, 2024 (publication date) through Dec 21, 2024

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. May 5, 2024; 15(2): 91591
Published online May 5, 2024. doi: 10.4292/wjgpt.v15.i2.91591

Table 2 Suggested table for documentation of treatment endpoints in ulcerative colitis

Time frame	Short term		Medium term		Long term
Proposed duration	6-8 wk		12-16 wk		26-52 wk
Endpoint type	Minimum endpoints	Ideal endpoints	Minimum endpoints	Ideal endpoints	Minimum endpoints	Ideal endpoints
Endpoints	Clinical response; Biochemical response; IUS response	Clinical remission; Biochemical remission; IUS remission	Clinical remission; IUS response; Endoscopic response	IUS remission; Endoscopic remission	Endoscopic remission; Histologic response	Endoscopic healing; Histologic healing; Gut barrier function restoration

It is recommended that endpoints in this table are re-evaluated periodically to either confirm or modify endpoints depending on individual patient factors. The above may be applicable for an otherwise healthy adult with ulcerative colitis. Ideal endpoints are in addition to minimum endpoints. IUS: Intestinal ultrasound.

Citation: Mitrev N, Kariyawasam V. Treatment endpoints in ulcerative colitis: Does one size fit all? World J Gastrointest Pharmacol Ther 2024; 15(2): 91591
URL: https://www.wjgnet.com/2150-5349/full/v15/i2/91591.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v15.i2.91591