Treatment endpoints in ulcerative colitis: Does one size fit all?

Table 1 Mean times (in weeks) for various induction therapies to reach a particular endpoint in ulcerative colitis

Therapy	Treatment endpoints
	Clinical response	Clinical remission	Normalisation CRP/ESR	Decrease of faecal calprotectin	Mucosal healing
Oral 5-aminosalicylates	4	8	8	10	13
Oral steroids	2	2	5	8	11
Locally acting steroids	3	8	8	9	13
Thiopurines	11	15	15	15	20
Adalimumab	6	11	10	12	14
Infliximab	5	10	9	11	13
Vedolizumab	9	14	14	15	18
Tofacitinib	6	11	9	11	14

CRP: C reactive protein; ESR: Erythrocyte sedimentation rate. Adapted from Turner et al[4], 2021.