Overweight and abdominal fat are associated with normal bone mineral density in patients with ulcerative colitis

Table 2 Demographic and clinical characteristics according to normal and low bone mineral density of patients with ulcerative colitis

Variable	Normal BMD (n = 40)	Low BMD (n = 28)	P value
Age (yr), median (IR)	37.5 (30.0-43.0)	40.0 (32.5-46.0)	0.193
Age group, n (%)
< 45 yr	31 (77.5)	20 (71.4)	0.57
≥ 45 yr	9 (22.5)	8 (28.6)
Sex, n (%)
Male	11 (27.5)	15 (53.6)	0.03
Female	29 (72.5)	13 (46.4)
Regular physical activity, n (%)
No	27 (67.5)	25 (89.3)	0.04
Yes	13 (32.5)	3 (10.7)
Duration of illness (yr), median (IR)	5.0 (2.0-9.0)	4.5 (1.2-6.7)	0.98
Extent of disease, n (%)
Proctitis	12 (30.0)	1 (3.6)	0.01
Left colitis	11 (27.5)	14 (50.0)
Extensive colitis	17 (42.5)	13 (46.4)
Use of glucocorticoids, n (%)
No	33 (84.6)	22 (78.6)	0.75
Yes	6 (15.4)	6 (21.4)
Use of glucocorticoids ≥ 3 mo, n (%)
No	3 (50.0)	1 (16.7)	0.54
Yes	3 (50.0)	5 (83.3)
Accumulated dose of glucocorticoids (g), median (IR)	1.8 (1.3-2.3)	1.5 (1.1-3.5)	0.55
Serum calcium (mmol/L), median (IR)	2.3 (2.3-2.4)	2.2 (2.2-2.3)	0.03
Serum albumin (g/dL), median (IR)	4.4 (4.1-4.6)	4.3 (4.0-4.5)	0.57
PCR mg/dL, median (IR)	3.1 (0.9-6.1)	1.6 (1.6-6.3)	0.56

SD: Standard deviation; IR: Interquartile range; BMD: Bone mineral density; C-RP: C-reactive protein.