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©The Author(s) 2022.
World J Gastrointest Pharmacol Ther. Jul 5, 2022; 13(4): 57-66
Published online Jul 5, 2022. doi: 10.4292/wjgpt.v13.i4.57
Published online Jul 5, 2022. doi: 10.4292/wjgpt.v13.i4.57
Table 1 Demographic, clinical, nutritional, and bone density characteristics of patients with ulcerative colitis
| Variable | UC (n = 68) | Control (n = 66) | P value |
| Age (yr), median (IR) | 39.0 (31.0-44.8) | 36.5 (29.0-43.0) | 0.484 |
| Sex (female), n (%) | 42 (61.8) | 39 (59.1) | 0.867 |
| Smoking (yes), n (%) | 2 (2.9) | 4 (6.1) | 0.437 |
| Regular physical activity (yes), n (%) | 16 (23.5) | 15 (22.7) | 1.000 |
| Duration of illness (yes), median (IR) | 5.0 (2.0-8.0) | ||
| Disease remission (yes), n (%) | 66 (97.1) | ||
| Intestinal resection history (yes), n (%) | 2 (2.9) | ||
| Extent of disease, n (%) | |||
| Proctitis | 13 (19.1) | ||
| Left colitis | 25 (36.8) | ||
| Extensive colitis | 30 (44.1) | ||
| Use of glucocorticoids (yes), n (%) | 12 (17.6) | ||
| Use ≥ 3 mo (yes), n (%) | 8 (66.7) | ||
| Accumulated dose of glucocorticoids (g), median (IR) | 1.7 (1.2-2.5) | ||
| Calcium supplement (yes), n (%) | 3 (4.4) | 0 (0) | 0.245 |
| Vit D supplement (yes), n (%) | 5 (7.4) | 0 (0) | 0.058 |
| Serum calcium (mmol/L), median (IR) | 2.3 (2.2-2.4) | 2.4 (2.3-2.4) | 0.065 |
| Serum albumin (g/dL), median (IR) | 4.3 (4.1-4.5) | 4.4 (4.1-4.6) | 0.801 |
| C-RP mg/dL, median (IR) | 1.4 (0.6-5.2) | 5.0 (1.0-6.2) | 0.004 |
| BMI (kg/m2), median (IR) | 23.7 (20.6-26.5) | 26.3 (22.8-29.0) | 0.16 |
| BMI classification, n (%) | 0.020 | ||
| Thinness | 5 (7.4) | 1 (1.5) | |
| Eutrophy | 40 (58.8) | 26 (39.4) | |
| Overweight | 16 (23.5) | 28 (42.4) | |
| Obesity | 7 (10.3) | 11 (16.7) | |
| WC (cm), median (IR) | 80.5 (72.0-89.1) | 84.6 (79.7-93.7) | 0.156 |
| LBM (kg), median (IR) | 40.1 (34.5-49.4) | 41.5 (35.3-52.2) | 0.604 |
| BF (kg), median (IR) | 17.8 (11.5-22.6) | 23.2 (17.8-28.4) | 0.001 |
| BF (%), median (IR) | 32.9 (23.7-37.6) | 34.8 (28.1-42.3) | 0.168 |
| TBF (kg), median (IR) | 8.6 (6.3-12.5) | 12.8 (7.8-16.5) | 0.354 |
| BMD (g/cm2), median (IR) | |||
| Femoral neck | 0.99 (0.90-1.07) | 1.06 (0.96-1.15) | 0.120 |
| Lumbar spine | 1.16 (1.08-1.26) | 1.21 (1.13-1.31) | 0.120 |
| Total body | 1.17 (1.11-1.24) | 1.22 (1.19-1.29 | 0.000 |
- Citation: Lopes MB, Lyra AC, Rocha R, Coqueiro FG, Lima CA, de Oliveira CC, Santana GO. Overweight and abdominal fat are associated with normal bone mineral density in patients with ulcerative colitis. World J Gastrointest Pharmacol Ther 2022; 13(4): 57-66
- URL: https://www.wjgnet.com/2150-5349/full/v13/i4/57.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v13.i4.57