Shared changes in angiogenic factors across gastrointestinal vascular conditions: A pilot study

doi:10.4292/wjgpt.v11.i3.40

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pharmacol Ther. Aug 8, 2020; 11(3): 40-47
Published online Aug 8, 2020. doi: 10.4292/wjgpt.v11.i3.40

Table 2 Levels of serum angiogenic factors according to group

	SBA	PHG	GAVE	Control
Ang-1 (ng/mL), mean (range)	35696 (12466-54338)	23111 (1950-72445)	30753 (9773-72609)	53115 (28624-82066)
P value vs controls	0.01	0.0003	0.01
Ang-2 (ng/mL), mean (range)	2803 (125-13141)	4298 (1299-8702)	4232 (1253-6081)	1899 (742-3693)
P value vs controls	0.4	0.0008	0.003
VEGF (ng/mL), mean (range)	443 (273-964)	316 (51-600)	435 (288-637)	421 (250-678)
P value vs controls	0.8	0.08	0.8
Ang-1/Ang-2 ratios by group	13	5	7	28
Median Ang-1/Ang-2 ratios	8			28
P value vs controls	0.001

SBA: Small bowel angiodysplasia; PHG: Portal hypertensive gastropathy; GAVE: Gastric antral vascular ectasia; VEGF: Vascular endothelial growth factor; Ang-1: Angiopoietin 1; Ang-2: Angiopoietin 2.

Citation: Douglas AR, Holleran G, Smith SM, McNamara D. Shared changes in angiogenic factors across gastrointestinal vascular conditions: A pilot study. World J Gastrointest Pharmacol Ther 2020; 11(3): 40-47
URL: https://www.wjgnet.com/2150-5349/full/v11/i3/40.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v11.i3.40