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World J Gastrointest Pharmacol Ther. Oct 6, 2010; 1(5): 112-118
Published online Oct 6, 2010. doi: 10.4292/wjgpt.v1.i5.112
Published online Oct 6, 2010. doi: 10.4292/wjgpt.v1.i5.112
Table 1 Mean pharmacokinetic parameters of the test and the reference formulations, each containing 10 mg lafutidine
| Parameters | Test (mean ± SD) | Reference (mean ± SD) |
| Cmax (ng/mL) | 265.15 ± 49.84 | 246.79 ± 29.30 |
| AUC(0-t) (ng.h /mL) | 1033.13 ± 298.74 | 952.94 ± 244.07 |
| AUC(0-∞) (ng.h/mL) | 1047.61 ± 301.22 | 964.22 ± 246.45 |
| tmax (h) | 0.95 ± 0.24 | 1.01 ± 0.29 |
| Kel (h-1) | 0.44 ± 0.19 | 0.42 ± 0.22 |
| t½ (h) | 1.92 ± 0.94 | 2.05 ± 1.05 |
- Citation: Dewan B, Chimata R. An open-label, randomized, cross-over bioequivalence study of lafutidine 10 mg under fasting condition. World J Gastrointest Pharmacol Ther 2010; 1(5): 112-118
- URL: https://www.wjgnet.com/2150-5349/full/v1/i5/112.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v1.i5.112