Effect of anesthetics on gastric damage using two models of portal hypertension

Figure 2 Gastric blood flow responses by topical application of ethanol (40%) in control (A), bile duct ligation (B) and portal vein stenosis (C) rats. A: Under both sodium pentobarbitone and ketamine/xylazine anesthesia, a reduction in gastric blood flow (GBF) was observed in control rats followed by hyperemic response of the gastric microcirculation (n = 5); B: GBF responses were absent in bile duct ligation rats under sodium pentobarbitone anesthesia whereas ketamine/xylazine anesthesia partially restored GBF responses to ethanol (n = 5); C: GBF rates increased in portal vein stenosis rats under sodium pentobarbitone anesthesia while under ketamine/xylazine anesthesia was reduced (n = 5).