Effects of commercially produced almond by-products on chemotherapy-induced mucositis in rats

Table 2 Effects of almond extracts on organ weights of female Dark Agouti rats 72 hr after 5-fluorouracil or saline injection

	Sal+PBS	Sal+ AHE1	Sal+ AHE2	Sal+ABW1	Sal+ ABW2	5-FU+PBS	5-FU+AHE1	5-FU+AHE2	5-FU+ ABW1	5-FU+ ABW2	5-FU+AHE2
Thymus	20 ± 1	21 ± 1	19 ± 1	20 ± 1	21 ± 1	10 ± 2b	10 ± 3b	8 ± 1b	8 ± 1b	10 ± 3b	8 ± 1b
Heart	40 ± 1	40 ± 1	42 ± 1	41 ± 1	42 ± 1	40 ± 2	43 ± 3	42 ± 1	40 ± 1	40 ± 3	42 ± 1
Lung	64 ± 3	74 ± 8	67 ± 3	69 ± 2	71 ± 4	77 ± 4	71 ± 6	72 ± 5	78 ± 1	77 ± 5	72 ± 5
Liver	374 ± 16	361 ± 13	372 ± 10	358 ± 11	380 ± 8	360 ± 14	383 ± 21	384 ± 9	380 ± 12	416 ± 16ad	384 ± 9
Stomach	58 ± 4	62 ± 2	64 ± 2	52 ± 5	57 ± 4	58 ± 5	63 ± 5	60 ± 4	55 ± 5	52 ± 5	60 ± 4
Caecum	40 ± 2	35 ± 4	38 ± 2	37 ± 1	38 ± 2	55 ± 5b	48 ± 4a	46 ± 4a	57 ± 2b	51 ± 5a	46 ± 4a
Spleen	23 ± 1	27 ± 2	24 ± 1	26 ± 2	25 ± 2	18 ± 1a	18 ± 1a	17 ± 1b	17 ± 1b	18 ± 1a	17 ± 1c
Left kidney	41 ± 2	43 ± 2	42 ± 1	40 ± 1	40 ± 1	40 ± 1	43 ± 2	41 ± 1	42 ± 1	43 ± 1	41 ± 1
Right kidney	42 ± 2	44 ± 2	43 ± 1	41 ± 1	42 ± 1	44 ± 1	43 ± 1	44 ± 1	42 ± 1	43 ± 1	44 ± 1
Adrenal glands	3 ± 1	3 ± 1	3 ± 1	2 ± 1	3 ± 1	3 ± 1	8 ± 1	3 ± 5	7 ± 4	3 ± 1	3 ± 5

Organ weights are expressed as % (wtg/gbwt). Data are expressed as means ± SEM.

^aP < 0.05 vs saline + PBS,

^bP < 0.01 vs saline + PBS,

^cP < 0.05 vs 5-FU + PBS,

^dP < 0.01 vs 5-FU + PBS. All values are 10^-2. 5-FU: 5-fluorouracil; PBS: Phosphate-buffered saline; AHE: Almond hull extract; ABW: Almond blanched water.