Effect of replenishment of vitamin D on survival in patients with decompensated liver cirrhosis: A prospective study

Table 4 Factors associated with survival

Methods, variables [mean (CI)]	Univariate analysis		Multivariate analysis
	Crude HR (95%CI)	P value	Adjusted HR (95%CI)	P value
Hepatic encephalopathy	1.53 (1.15-2.01)	< 0.05
Bilirubin	1.04 (1.01-1.08)	< 0.05	0.90 (0.83-0.98)	< 0.05
AST	1.00 (0.99-1.00)	> 0.05
Creatinine	228 (21-2445)	< 0.05	57.43 (2.16-1522)	< 0.05
PT-INR	6.63 (2.52-17.5)	< 0.05
Ascitic fluid TLC	1.004 (1.002-1.006)	< 0.05	1.02 (1.00-1.04)	< 0.05
Blood TLC	1.00 (0.99-1.00)	> 0.05
Serum Sodium	0.92 (0.87-0.97)	< 0.05
Treatment with VD	0.92 (0.81-1.03)	> 0.05	0.46 (0.22-0.95)	< 0.05
CTP score	2.21 (1.69-2.89)	< 0.05	1.39 (1.00-1.95)	< 0.05
MELD score	1.34 (1.23-1.47)	< 0.05	1.60 (1.26-2.02)	< 0.05

PT: Prothrombin time; AST: Aspartate aminotransferase; VD: Vitamin D; CTP: Child Turcott Pugh; MELD: Model for end-stage liver disease.