Embrionary way to create a fatty liver in portal hypertension

Figure 7 The recapitulated systemic extra-embryonic functions, that is, the coelomic-amniotic and the trophoblastic-yolk sac (or vitellum), are located into the space of Disse. This fact results in the development of hepatic steatosis and steatohepatitis in prehepatic portal hypertensive rats. A: Amnion; ANS: Autonomic nervous system; BD: Bile duct; BI: Blood islands; CNS: Central nervous system; EM: Extraembryonic mesoderm; HA: Hepatic artery; HS: Steatotic liver; HSC: Hematological stem cell; HV: Hepatic vein; MSC: Mesenchymal stem cell; TPVL: Triple partial portal vein ligation; Y: Yolk sac.