Clinical impacts of mesothelin expression in gastrointestinal carcinomas

doi:10.4291/wjgp.v7.i2.218

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. May 15, 2016; 7(2): 218-222
Published online May 15, 2016. doi: 10.4291/wjgp.v7.i2.218

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Figure 1 Schematics showing the maturation of mesothelin protein. The primary product of the full-ERC/mesothelin gene is a 71-kDa precursor protein. This protein is physiologically cleaved, releasing a 31-kDa fragment, N-ERC/mesothelin, into the blood. MPF: Megakaryocyte potentiating factor; SMRP: Soluble mesothelin-related peptide; GPI: Glycosylphosphatidylinositol.

Citation: Einama T, Kawamata F, Kamachi H, Nishihara H, Homma S, Matsuzawa F, Mizukami T, Konishi Y, Tahara M, Kamiyama T, Hino O, Taketomi A, Todo S. Clinical impacts of mesothelin expression in gastrointestinal carcinomas. World J Gastrointest Pathophysiol 2016; 7(2): 218-222
URL: https://www.wjgnet.com/2150-5330/full/v7/i2/218.htm
DOI: https://dx.doi.org/10.4291/wjgp.v7.i2.218