Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine

Table 3 Significantly enriched Gene Ontology categories

GO category	P-value	Enrichment	(N, B, n, b)
Single ranked list
GO:0008236 Serine-type peptidase activity	3.38E-14	35.6	(13551, 135, 31, 11)
GO:0008233 Peptidase activity	7.66E-11	12.6	(13551, 451, 31, 13)
GO:0007586 Digestion	1.82E-10	209.8	(13551, 19, 17, 5)
GO:0007600 Sensory perception	3.45E-8	1.67	(13551, 817, 1270, 128)
GO:0006508 Proteolysis	4.01E-8	7.65	(13551, 743, 31, 13)
GO:0004984 Olfactory receptor activity	7.11E-8	1.82	(13551, 552, 1270, 94)
GO:0004806 Triglyceride lipase activity	7.01E-7	271.0	(13551, 10, 15, 3)
GO:0004930 GPCR activity	3.86E-5	2.41	(13551, 512, 352, 32)
Two unranked lists (target and background)
GO:0008236 Serine-type peptidase activity	6.03E-8	4.63	(13551, 135, 390, 18)
GO:0007586 Digestion	5.79E-7	12.8	(13551, 19, 390, 7)
GO:0004930 GPCR activity	1.30E-5	2.24	(13551, 512, 390, 33)
GO:0004984 Olfactory receptor activity	5.86E-5	2.08	(13551, 552, 390,3 3)
GO:0004806 Triglyceride lipase activity	1.24E-4	13.9	(13551, 10, 390, 4)
GO:0008233 Peptidase activity	2.71E-4	2.08	(13551, 451, 390, 27)

GO categories were identified using both the Single rank and Two unranked list options of the GOrilla Gene Ontology program[9]. N is the total number of genes, B is the total number of genes associated with a specific GO term, n is the number of genes in the target set, b is the number of genes in the intersection. Enrichment = (b/n)/(B/N). GPCR: G-protein coupled receptor; GO: Gene Ontology.