Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine

Table 2 Genes with the highest levels of differential expression in the Nkcc1-null intestine

Gene symbol	Description	Average intensity	Fold change	P value
Cpa1	Carboxypeptidase A1, pancreatic	1811	15.86	0.00001
Elane	Elastase 2	2118	12.05	0.00001
Glb1l3	Galactosidase, beta 1 like 3	234	10.27	0.0001
Try4	Trypsin 4	2251	9.91	0.00001
Rnase1	Ribonuclease 1, pancreatic RNase A	592	9.28	0.00001
Cpb1	Carboxypeptidase B1	866	9.15	0.00001
Amy2a5	Amylase 2, pancreatic	691	8.75	0.00001
Try10	Trypsin 10	2306	8.33	0.00001
Ctrc	Chymotrypsin C (caldecrin)	397	7.79	0.0003
Ctrb1	Chymotrypsinogen B1	3360	7.66	0.00001
Pnlip	Pancreatic lipase	1938	7.24	0.00001
Prss1	Protease, serine 1 (trypsin 1)	1481	6.93	0.00001
Cel	Bile salt activated lipase, pancreatic	356	6.73	0.00001
Cela3b	Elastase 3B, pancreatic	1576	6.69	0.00001
Prss2	Protease, serine 2 (trypsin II)	716	6.52	0.0001
Pnliprp1	Pancreatic lipase related protein 1	574	5.83	0.0001
Muc6	Mucin 6, gastric	152	5.78	0.0053
Tff2	Trefoil factor 2	1391	5.77	0.0200
Cela1	Elastase 1, pancreatic	549	4.84	0.0002
V1rh10	Vomeronasal 1 receptor, H10	107	4.66	0.0008
Calb3	Calbindin D9K	609	4.64	0.00001
Reg1	Lithostathine 1 (pancreatic stone protein 1)	5648	4.56	0.0008
Pdia2	Protein disulfide isomerase, pancreatic	292	4.47	0.0004
Akp3	Alkaline phosphatase 3, intestine	366	4.02	0.00001
Gp2	Glycoprotein 2 (zymogen granule membrane)	377	3.92	0.0001
Cep350	Centrosomal protein 350	141	3.92	0.0003
Bmper	BMP-binding endothelial regulator	318	3.78	0.0011
Olfr846	Olfactory receptor 846	432	3.66	0.0001
Reg2	Lithostathine 2 (pancreatic stone protein 2)	253	3.58	0.0383
Ctrl	Chymotrypsin like; chymotrypsin A	1431	3.49	0.0030

Differential expression is presented as fold-changes in Nkcc1^-/- intestine relative to wild-type intestine. Average intensity (average of Cy3 and Cy5 fluorescence intensities) is roughly indicative of relative expression levels. P values are less than or equal to the numbers shown.