Role of anti-stromal polypharmacy in increasing survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma

doi:10.4291/wjgp.v6.i4.235

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Nov 15, 2015 (publication date) through Nov 30, 2024

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Nov 15, 2015; 6(4): 235-242
Published online Nov 15, 2015. doi: 10.4291/wjgp.v6.i4.235

Table 5 Kaplan-Meier survival estimates and multivariate cox regression comparing patients taking a combination of calcium channel blockers + aspirin with patients on one or neither drug

Drug group	Number of people	Estimated median	P-value (log rank)	Multivariate cox regression
	in group	survival (d)	compared to control	HR (95%CI)	P-value
Control (no CCB/aspirin)	98	601	-	1	-
CCB + aspirin	15	1414	0.029	0.332 (0.126-0.870)	0.025
Aspirin without CCB	40	392	0.032	1.658 (0.968-2.840)	0.066
CCB without Aspirin	11	343	0.563	1.039 (0.416-2.595)	0.935

CCB: Calcium channel blockers.

Citation: Tingle SJ, Moir JA, White SA. Role of anti-stromal polypharmacy in increasing survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. World J Gastrointest Pathophysiol 2015; 6(4): 235-242
URL: https://www.wjgnet.com/2150-5330/full/v6/i4/235.htm
DOI: https://dx.doi.org/10.4291/wjgp.v6.i4.235