Altered molecular pattern of mucosal healing in Crohn’s disease fibrotic stenosis

Figure 1 Levels of the three investigated molecules. A: Specimens with complicated Crohn’s disease and controls. The levels of tumor necrosis factor (TNF)-α do not show a significant difference from that observed in normal tissue (1.54 ± 1.19; P > 0.05). High levels of basic fibroblast growth factor (bFGF) are observed in Crohn’s disease (11.76 ± 4.65; P < 0.001), while syndecan 1 shows a moderate increase (5.53 ± 2.18; P < 0.005). Analysis of variance plus Student-Neumann-Keuls showed: bFGF > syndecan 1; B: The same parameters on the bases of their site (small and large bowel). No significant difference is observed in relation to the site of resection.