Importance of histological evaluation in endoscopic resection of early colorectal cancer

Figure 3 A submucosally invasive cancer with unidentifiable muscularis mucosae. A: Submucosal invasion (black arrow) with complete destruction of the muscularis mucosae was detected by histological examination of hematoxylin and eosin stained sections; B: Immunohistological staining for desmin showed that the muscularis mucosae could not be identified. The depth of submucosal invasion was 3500 μm (black arrow).