Review
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastrointest Pathophysiol. Feb 15, 2012; 3(1): 27-43
Published online Feb 15, 2012. doi: 10.4291/wjgp.v3.i1.27
Table 1 Functions of commensal bacteria in the gut
Protective functions Pathogen displacement Competition for nutrients Competition for receptors Production of anti-microbial factors
Metabolic functions Fermentation of non-digestible dietary substances Generation of short chain fatty acids Salvage of energy source Synthesis of essential vitamins (vitamin K and B12, niacin, biotin and folate)
Structural functions Regulation of epithelial cell turnover Promotion of epithelial cell differentiation Fortification of epithelial barrier Stabilization of tight junctions
Immune functions Induction of secretory IgA Induction of oral tolerance Shaping of immune microenvironment