Treatment strategy for gastric non-invasive intraepithelial neoplasia diagnosed by endoscopic biopsy

Table 4 Endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer[60]

	EMR	ESD
Merits	Minimally invasive technique which is safe, convenient and efficacious	The advantage of achieving large en-bloc resections, not necessarily limited by lesion size
Demerits	Insufficient when treating larger lesions, especially larger that 15 mm	Requiring significant additional technical skills and a longer procedure time
		Prolonged learning curve
	High risks of local recurrence, especially when resections are not performed en bloc or when the resection margins are involved by tumor	A higher complication rate compared to standard EMR

ESD: Endoscopic submucosal dissection; EMR: Endoscopic mucosal resection.