Treatment strategy for gastric non-invasive intraepithelial neoplasia diagnosed by endoscopic biopsy

doi:10.4291/wjgp.v2.i6.93

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Dec 15, 2011; 2(6): 93-99
Published online Dec 15, 2011. doi: 10.4291/wjgp.v2.i6.93

Table 2 Histological discrepancy rates between biopsy and endoscopic resection sample n (%)

Reports (yr)	Endoscopic biopsy	Resected specimens		Overall
		Underdiagnosis¹	Overdiagnosis²	Discrepancy³
Yoon et al[47], 2006	Tubular adenoma	2/41 (4.9)	2/41 (4.9)	4/41 (9.8)
Jung et al[29], 2008	LGIN	31/74 (42)	-	-
	HGIN	36/40 (90)	2/40 (5)	38/40 (95)
Lee et al[48], 2010	IN	114/311 (37)	41/311 (13)	155/311 (50)
	Carcinoma	7/86 (8.1)	16/86 (19)	23/86 (26)
	Total	121/397 (30)	57/397 (14)	178/397 (45)
Kato et al[27], 2010	IN	255/468 (44)	4/468 (1.7)	259/468 (46)

¹Underdiagnosis was defined as if endoscopic biopsy showed tubular adenoma/ intraepithelial neoplasia but resected specimens finally led to the diagnosis of adenocarcinoma/carcinoma;

²Overdiagnosis was defined as if endoscopic biopsy showed tubular adenoma/intraepithelial neoplasia or adenocarcinoma/carcinoma but resected specimens finally led to the diagnosis of non-neoplastic, reactive, regenerative or tubular adenoma, respectively;

³Discrepancy was defined as if endoscopic biopsy does not correspond with resected specimen. This can be calculated using resected specimen as a golden standard. LGIN: Low-grade intraepithelial neoplasia; IN: Intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia.

Citation: Nishida T, Tsutsui S, Kato M, Inoue T, Yamamoto S, Hayashi Y, Akasaka T, Yamada T, Shinzaki S, Iijima H, Tsujii M, Takehara T. Treatment strategy for gastric non-invasive intraepithelial neoplasia diagnosed by endoscopic biopsy. World J Gastrointest Pathophysiol 2011; 2(6): 93-99
URL: https://www.wjgnet.com/2150-5330/full/v2/i6/93.htm
DOI: https://dx.doi.org/10.4291/wjgp.v2.i6.93