Janice Drew’s work on diet and cancer

Figure 2 Obesity cancer links. Obesity and colon cancer are both associated with increased consumption of diets rich in saturated fats, together with reduced consumption of fruit, vegetables and fibre. Consumption of high fat diets and diets deficient in fruit, vegetables and fibre promotes metabolic stress. This is manifested by increased oxidative stress and inflammatory responses, altered levels of adipokines, insulin and triglycerides and changes in protein profiles of mitochondrial multiple protein expression forms (MPEFs). Research investigating the metabolic changes associated with obesity is elucidating molecular mechanisms linked to associated increased cancer risk