Team players in the pathogenesis of metabolic dysfunctions-associated steatotic liver disease: The basis of development of pharmacotherapy

Figure 6 Overview of PPARγ function and mechanisms in the different cell types[256]. Schematic representation of PPARγ in adipocytes (white, beige, and brown adipocytes), immune cells (macrophages, dendritic cells, and T cells), and cancer cells. Indicated are different cellular processes and mechanisms of action in which PPARγ is involved. WAT: White adipose tissue; BAT: Brown adipose tissue; TNF: Tumor necrosis factor-alpha; IL: Interleukin; IFN-γ: Interferon gamma. Citation: Hernandez-Quiles M, Broekema MF, Kalkhoven E. PPARgamma in Metabolism, Immunity, and Cancer: Unified and Diverse Mechanisms of Action. Front Endocrinol (Lausanne) 2021; 12: 624112 Copyright © Hernandez-Quiles, Broekema and Kalkhoven. Published by Hernandez-Quiles, Broekema and Kalkhoven.