Novel, non-colonizing, single-strain live biotherapeutic product ADS024 protects against Clostridioides difficile infection challenge in vivo

doi:10.4291/wjgp.v14.i4.71

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Aug 24, 2023 (publication date) through Jul 22, 2024

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Aug 24, 2023; 14(4): 71-85
Published online Aug 24, 2023. doi: 10.4291/wjgp.v14.i4.71

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Figure 5 The impact of ADS024 on microbiota diversity in the miniature swine fecal samples during the 28-d study. MiSeq compositional sequencing and bioinformatic analysis were performed to measure the impact of ADS024 on the microbiota in miniature swine fecal samples after 28 d using the: A: Shannon index for alpha diversity; B: Simpson diversity index for alpha diversity; C: UniFrac principal coordinates analysis (PCoA) for beta diversity.

Citation: Murphy CK, O’Donnell MM, Hegarty JW, Schulz S, Hill C, Ross RP, Rea MC, Farquhar R, Chesnel L. Novel, non-colonizing, single-strain live biotherapeutic product ADS024 protects against Clostridioides difficile infection challenge in vivo. World J Gastrointest Pathophysiol 2023; 14(4): 71-85
URL: https://www.wjgnet.com/2150-5330/full/v14/i4/71.htm
DOI: https://dx.doi.org/10.4291/wjgp.v14.i4.71