Copyright
©The Author(s) 2023.
World J Gastrointest Pathophysiol. Jun 1, 2023; 14(3): 46-70
Published online Jun 1, 2023. doi: 10.4291/wjgp.v14.i3.46
Published online Jun 1, 2023. doi: 10.4291/wjgp.v14.i3.46
Figure 2 Regulation of p53.
p53 is a tumour suppressor protein which leads to increase in the apoptosis markers like Bax, cytochrome C and caspase 3. As murine double minute 2 complexes with p53 it leads to ubiquitination of p53 and proteasomal degradation takes place (Created with BioRender.com). MDM2: Murine double minute 2.
- Citation: Choudhary HB, Mandlik SK, Mandlik DS. Role of p53 suppression in the pathogenesis of hepatocellular carcinoma. World J Gastrointest Pathophysiol 2023; 14(3): 46-70
- URL: https://www.wjgnet.com/2150-5330/full/v14/i3/46.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v14.i3.46