Polymorphism of genes encoding drug-metabolizing and inflammation-related enzymes for susceptibility to cholangiocarcinoma in Thailand

doi:10.4291/wjgp.v14.i2.21

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Mar 22, 2023 (publication date) through Dec 29, 2024

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Gastrointest Pathophysiol. Mar 22, 2023; 14(2): 21-33
Published online Mar 22, 2023. doi: 10.4291/wjgp.v14.i2.21

Table 2 Relationship between serum anti-Opisthorchis viverrini and cholangiocarcinoma risk, Ubon Ratchathani, Thailand

Number of case-control pairs according to serum anti-OV status: positive (+) vs negative (-)				Crude OR	95%CI		P value	Adjusted¹ OR	95%CI		P value	Adjusted² OR	95%CI		P value
Case (+) / Control (+)	Case (+) / Control (-)	Case (-) / Control (+)	Case (-) / Control (-)	Crude OR	LL	UL	P value	Adjusted¹ OR	LL	UL	P value	Adjusted² OR	LL	UL	P value
67	23	2	3	11.50	2.71	48.78	< 0.001	8.96	2.06	38.99	0.001	9.40	2.16	40.85	0.003

¹Adjusted for alcohol consumption and smoking.

²Adjusted for alcohol consumption and smoking. Missing values for these variables were imputed.

OV: Opisthorchis viverrini; CCA: Cholangiocarcinoma; LL: Lower limit; UL: Upper limit.

Citation: You G, Zeng L, Tanaka H, Ohta E, Fujii T, Ohshima K, Tanaka M, Hamajima N, Viwatthanasittiphong C, Muangphot M, Chenvidhya D, Jedpiyawongse A, Sripa B, Miwa M, Honjo S. Polymorphism of genes encoding drug-metabolizing and inflammation-related enzymes for susceptibility to cholangiocarcinoma in Thailand. World J Gastrointest Pathophysiol 2023; 14(2): 21-33
URL: https://www.wjgnet.com/2150-5330/full/v14/i2/21.htm
DOI: https://dx.doi.org/10.4291/wjgp.v14.i2.21