Chemokine receptor 8 expression may be linked to disease severity and elevated interleukin 6 secretion in acute pancreatitis

doi:10.4291/wjgp.v12.i6.115

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Nov 22, 2021 (publication date) through Dec 2, 2024

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Pathophysiol. Nov 22, 2021; 12(6): 115-133
Published online Nov 22, 2021. doi: 10.4291/wjgp.v12.i6.115

Table 3 Gene expression levels (fold change 2^{^-ΔΔCT}) for chemokine receptor 8 gene in acute pancreatitis patients.

Severity	Mean fold change (2^{^-ΔΔCT})
MAP D3	0.8 ± 0.22
MAP D5	0.9 ± 0.25
MAP D7	1.0 ± 0.26
MSAP D3	1386 ± 1372
MSAP D5	68.0 ± 67
MSAP D7	848 ± 846
SAP D3	1090632 ± 1090631
SAP D5	1.1, NA
SAP D7	1.3 ± 0.46

MAP: Mild acute pancreatitis; MSAP: Moderately severe acute pancreatitis; SAP: Severe acute pancreatitis. D: Day; D3: Day 3 post epigastric pain; CCR8: Chemokine receptor 8; 2^{^-ΔΔCT}: Fold change, is used to measure change in the expression level of a gene[32]; NA: Not available due to single data points.

Citation: Nalisa M, Nweke EE, Smith MD, Omoshoro-Jones J, Devar JW, Metzger R, Augustine TN, Fru PN. Chemokine receptor 8 expression may be linked to disease severity and elevated interleukin 6 secretion in acute pancreatitis. World J Gastrointest Pathophysiol 2021; 12(6): 115-133
URL: https://www.wjgnet.com/2150-5330/full/v12/i6/115.htm
DOI: https://dx.doi.org/10.4291/wjgp.v12.i6.115