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©The Author(s) 2021.
World J Gastrointest Pathophysiol. Sep 22, 2021; 12(5): 84-105
Published online Sep 22, 2021. doi: 10.4291/wjgp.v12.i5.84
Published online Sep 22, 2021. doi: 10.4291/wjgp.v12.i5.84
Figure 1 Major signalling pathways involved in cholangiocarcinoma.
The major signaling pathways involved in cholangiocarcinomas could be categorized into three main class: (1) Microenvironment and inflammation-related pathways; (2) Pathways related to proliferation/survival/death; and (3) Development-related pathways. TGF-β: Transforming growth factor-β; CCA: Cholangiocarcinoma; IL: Interleukin; FGFR2: Fibroblast growth factor receptor 2; PI3K: Phosphatidylinositol 3 kinase; ERK: Extracellular signal-regulated kinase; JAK/STAT: Janus kinase and signal transducer and activator of transcription.
- Citation: Safarpour AR, Askari H, Ejtehadi F, Azarnezhad A, Raeis-Abdollahi E, Tajbakhsh A, Abazari MF, Tarkesh F, Shamsaeefar A, Niknam R, Sivandzadeh GR, Lankarani KB, Ejtehadi F. Cholangiocarcinoma and liver transplantation: What we know so far? World J Gastrointest Pathophysiol 2021; 12(5): 84-105
- URL: https://www.wjgnet.com/2150-5330/full/v12/i5/84.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v12.i5.84