Evaluation of bacterial biomarkers to aid in challenging inflammatory bowel diseases diagnostics and subtype classification

Figure 1 Usefulness of Faecalibacterium prausnitzii, its phylogroups (PHGI and PHGII) and their index in conjunction to Escherichia coli to discriminate between milder gut conditions [Healthy controls (H) and irritable bowel syndrome] and inflammatory bowel disease (ulcerative colitis and Crohn’s disease) by pooling all biopsy samples together (A), by location of sampling (B) and by activity status (C). Best area under the receiver operating characteristic curve (AUC) values for each comparison are shown. FP: Faecalibacterium prausnitzii; UC: Ulcerative colitis; CD: Crohn’s disease; IBS: Irritable bowel syndrome.