Editorial
Copyright ©2010 Baishideng Publishing Group Co.
World J Gastrointest Pathophysiol. Dec 15, 2010; 1(5): 147-153
Published online Dec 15, 2010. doi: 10.4291/wjgp.v1.i5.147
Table 1 Molecular and biochemical characteristics of free fatty acid receptors and GPR120
ReceptorLocalizationLigandSignaling
FFAR119q13.1> C6; medium to long chainInsulin, GLP-1, GIP
FFAR219q13.1C2-C6; acetate, propionate, butyratePYY, 5-HT
FFAR319q13.1C2-C6; propionate > butyrate > acetateLeptin, PYY
GPR12010q23.33Medium and long chain; alpha-linolenic acid, docosa- hexadienic acid, palmitoleic acidGLP-1, CKK