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World J Gastrointest Pathophysiol. Dec 15, 2010; 1(5): 147-153
Published online Dec 15, 2010. doi: 10.4291/wjgp.v1.i5.147
Published online Dec 15, 2010. doi: 10.4291/wjgp.v1.i5.147
Table 1 Molecular and biochemical characteristics of free fatty acid receptors and GPR120
Receptor | Localization | Ligand | Signaling |
FFAR1 | 19q13.1 | > C6; medium to long chain | Insulin, GLP-1, GIP |
FFAR2 | 19q13.1 | C2-C6; acetate, propionate, butyrate | PYY, 5-HT |
FFAR3 | 19q13.1 | C2-C6; propionate > butyrate > acetate | Leptin, PYY |
GPR120 | 10q23.33 | Medium and long chain; alpha-linolenic acid, docosa- hexadienic acid, palmitoleic acid | GLP-1, CKK |
- Citation: Kaemmerer E, Plum P, Klaus C, Weiskirchen R, Liedtke C, Adolf M, Schippers A, Wagner N, Reinartz A, Gassler N. Fatty acid binding receptors in intestinal physiology and pathophysiology. World J Gastrointest Pathophysiol 2010; 1(5): 147-153
- URL: https://www.wjgnet.com/2150-5330/full/v1/i5/147.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v1.i5.147