Role of sex hormones in the modulation of cholangiocyte function

doi:10.4291/wjgp.v1.i2.50

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Jun 15, 2010 (publication date) through Nov 4, 2024

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Jun 15, 2010; 1(2): 50-62
Published online Jun 15, 2010. doi: 10.4291/wjgp.v1.i2.50

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Figure 1 Two-pathway theory of estrogen-receptor-dependent growth. Many estrogen target cells contain growth-stimulatory and -inhibitory pathways. Both pathways are mediated through ERs. Tamoxifen may possess relatively high affinity for the growth-inhibitory pathway whereas estrogen can mainly activate the growth-stimulatory pathway. However, any ligand for ER can stimulate both pathways.

Citation: Mancinelli R, Onori P, DeMorrow S, Francis H, Glaser S, Franchitto A, Carpino G, Alpini G, Gaudio E. Role of sex hormones in the modulation of cholangiocyte function. World J Gastrointest Pathophysiol 2010; 1(2): 50-62
URL: https://www.wjgnet.com/2150-5330/full/v1/i2/50.htm
DOI: https://dx.doi.org/10.4291/wjgp.v1.i2.50