Diffusion magnetic resonance imaging: A molecular imaging tool caught between hope, hype and the real world of “personalized oncology”

Figure 10 A 60-year-old female on tamoxifen, presented with post-menopausal bleeding. MRI revealed a heterogeneously hyperintense lesion in the endometrium (white arrow in A and B) which showed restricted diffusion (black arrow in C) with low ADC values (black arrow in D). Surgery was performed and histopathology showed tamoxifen induced hyperplasia harboring carcinoma of the endometrium. ADC: Apparent diffusion coefficient; MRI: Magnetic resonance imaging.