Lymph node imaging in initial staging of prostate cancer: An overview and update

Figure 2 Selected images from a ferumoxytol enhanced magnetic resonance imaging in a 65 years old man status post magnetic resonance imaging/ultrasound fusion guided prostate biopsy revealing 3 + 3 prostate cancer and PSA 16. 6 ng/mL. A: Baseline T2* weighted magnetic resonance imaging (MRI) showed a rounded lymph node anterior to the bladder (arrowhead) that measured 1.5 cm and was hyperintense. Lobular mass like lesion (arrow) lateral to the suspicious lymph node corresponds to hernia mesh; B: 24 h post injection of ferumoxytol (7.5 Fe/kg dose) enhanced MRI shows persistent heterogeneous hyperintensity within the node (arrowhead). The lack of ferumoxytol uptake within the node was suspicious for malignant involvement. Pathology revealed castleman's disease (false positive). Arrow again indicates hernia mesh.