Lymph node imaging in initial staging of prostate cancer: An overview and update

Figure 1 Selected imaged from a ferumoxytol enhanced magnetic resonance imaging in a 59-year-old man who underwent transrectal ultrasonography prostate biopsy for elevated PSA (10. 8 ng/mL) which showed Gleason 3 + 4 disease of 4 cores. A: Initial prostate multiparametric T1 weighted post gadolinium magnetic resonance imaging (MRI) showed a 1.8 cm × 0.9 cm right external iliac chain lymph node that was suspicious base on size criteria (arrowhead); B: 24 h post injection of ferumoxytol (7.5 Fe/kg dose), T2* weighted MRI showed decreased signal intensity within the node (arrowhead), consistent with uptake of ferumoxytol. This was considered a benign lymph node based on these results. The patient underwent computed tomography guided biopsy for confirmation and the node was negative for malignancy.