What can imaging tell us about cognitive impairment and dementia?

Figure 4 Underlying neuronal dysfunction and neurodegeneration. A: Hexamethylpropylene amine oxime (HMPAO) single photon emission computed tomography (SPECT) in normal control subject demonstrating normal almost symmetrical perfusion pattern; B: HMPAO SPECT in Alzheimer’s disease parametric images demonstrate bilateral reduction in perfusion in the temporal lobes especially in the medial temporal regions up to 2 (green) and 3 (blue) standard deviation (Images kindly prepared by Ms Lesley Lovell, Senior technician).