Grey-scale sonography and sonoelastography for diagnosing carpal tunnel syndrome

Table 3 Summary of studies reporting the diagnostic value of the cross-sectional area ratio of the median nerve for carpal tunnel syndrome

Ref.	CSA ratio cut-off	CTS wrists	Control wrists	Location	Sensitivity (%)	Specificity (%)	AUC
Hobson-Webb et al[21]	1.4	44	18	Distal wrist crease/12 cm proximal in the forearm	100	NA	NA
Visser et al[22]	2	265	137	Tunnel inlet/forearm	69	90	0.83
Roll et al[19]	1.70	83	83	Pisiform/6 cm proximal to the distal wrist crease	80.4	81.2	0.842
Kang et al[23]	1.34	110	38	Distal wrist crease/12 cm proximal in the forearm	99.9	100	0.988
Mhoon et al[24]	1.4	192	50	Distal wrist crease/12 cm proximal in the forearm	97	28	0.789
Fu et al[25]	1.3	46	44	Tunnel inlet/outlet	91	93	0.98

CSA: Cross-sectional area; CTS: Carpal tunnel syndrome; AUC: Area under curve; NA: Not available.