Comparisons between glucose analogue 2-deoxy-2-(18F)fluoro-D-glucose and 18F-sodium fluoride positron emission tomography/computed tomography in breast cancer patients with bone lesions

doi:10.4329/wjr.v8.i2.200

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Feb 28, 2016 (publication date) through Mar 10, 2025

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Radiol. Feb 28, 2016; 8(2): 200-209
Published online Feb 28, 2016. doi: 10.4329/wjr.v8.i2.200

Table 3 Sites and density characteristics showing different performance between 2-deoxy-2-(¹⁸F)fluoro-D-glucose and ¹⁸F-sodium positron emission tomography/computed tomography

	n	¹⁸F-FDG	¹⁸F-NaF	P
Density
Osteosclerotic	89			0.005
Sensitivity (%):		42.86 (15.82-74.95)	99.00 (64.57-99.00)
Specificity (%):		97.00 (60.97-97.00)	48.15 (35.39-61.15)
No lesion/bone marrow	29			0.002
Sensitivity(%):		100.00 (60.97-100.00)	48.15 (30.74-66.01)
Specificity(%):		100.00 (34.24-100.00)	100.00 (34.24-100.00)
Site
Spine	81			0.002
Sensitivity (%):		65.38 (51.80-76.85)	100.00 (93.12-100.00)
Specificity (%):		98.00 (88.30-98.00)	13.45 (0.61-27.18)
Ribs	118			0.04
Sensitivity (%):		83.96 (75.81-89.74)	96.23 (90.70-98.52)
Specificity (%):		78.37 (52.33-92.50)	78.57 (52.41-92.43)

¹⁸F-FDG: 2-deoxy-2-(¹⁸F)fluoro-D-glucose; ¹⁸F-NaF: ¹⁸F-sodium.

Citation: Capitanio S, Bongioanni F, Piccardo A, Campus C, Gonella R, Tixi L, Naseri M, Pennone M, Altrinetti V, Buschiazzo A, Bossert I, Fiz F, Bruno A, DeCensi A, Sambuceti G, Morbelli S. Comparisons between glucose analogue 2-deoxy-2-(¹⁸F)fluoro-D-glucose and ¹⁸F-sodium fluoride positron emission tomography/computed tomography in breast cancer patients with bone lesions. World J Radiol 2016; 8(2): 200-209
URL: https://www.wjgnet.com/1949-8470/full/v8/i2/200.htm
DOI: https://dx.doi.org/10.4329/wjr.v8.i2.200