Combined value of apparent diffusion coefficient-standardized uptake value max in evaluation of post-treated locally advanced rectal cancer

Table 4 Overview of studies analysing mean apparent diffusion coefficient and delta apparent diffusion coefficient values of the rectal lesion for each MR study

Ref.	n of patients	Pre ADC mean R	Pre ADC mean NR	Post ADC mean R	Post ADC mean NR	ROC curve (highest accuracy)
Ippolito et al[45]	30	0.88 ± 0.19	0.78 ± 0.09	1.47 ± 0.22	1.19 ± 0.20	1.28 (80%)
Kim et al[41]	34	0.90 ± 0.06	0.94 ± 0.03
Jung et al[37]	35	0.93 ± 0.09	1.03 ± 0.08	1.29 ± 0.13	1.18 ± 0.08	1.18 (77.1%)
Kim et al[6]	40			1.62 ± 0.36	1.04 ± 0.24	1.20 (85%)
Curvo Semedo et al[43]	50	1.07 ± 0.15	1.10 ± 0.19	1.39 ± 0.24	1.45 ± 0.28	1.41 (53%)
Ha et al[38]	100	0.59 ± 0.29	0.49 ± 0.22	1.33 ± 0.25	1.13 ± 0.32	1.20 (67%)
Genovesi[44]	28	1.01 ± 0.06	1.29 ± 0.02	1.79 ± 0.51	1.37 ± 0.43	29.5 (91.3%)
Cai et al[39]	15	0.659	0.885	0.713	1.027
Birlik et al[40]	43	0.66 ± 0.10	0.72 ± 0.14	1.22 ± 0.26	0.95 ± 0.20	1.20 (60%)

R: Responders; NR: Non responders; ADC: Apparent diffusion coefficient.