Feasibility study of computed vs measured high b-value (1400 s/mm²) diffusion-weighted MR images of the prostate

Figure 1 Axial T2-weighted image of an 88 years old patient with a PSA level of 8. 2 ng/mL and negative findings upon digital rectal examination. T2w shows a focal hypointense lesion in the posterolateral left midgland pz (arrowhead in A). Measured b-values of 0, 100, 400 and 800 s/mm² (arrowheads in B, C, D and E, respectively) do not depict the suspected lesion with sufficient contrast to background prostate. M-b1400 shows good lesion-to-prostate contrast (arrowhead in F). C-b1400 depicts the lesion with the same lesion-to-prostate contrast and a slightly improved demarcation (arrowhead in G). The ADC value of the suspicious lesion was as low as 648 × 10^-3 mm/s² [ADC map (H)].