Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders

doi:10.4329/wjr.v6.i10.756

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Radiol. Oct 28, 2014; 6(10): 756-778
Published online Oct 28, 2014. doi: 10.4329/wjr.v6.i10.756

Table 5 Parkinson’s disease deep brain stimulation targets-limbic effects

	STN_DBS
Prefrontal
Dorsolateral prefrontal cortex	↑Hilker¹^b
Lateral prefrontal cortex	↑Stefurak¹^b
Cingulate
Posterior cingulate	↓Stefurak¹^b; ↑Hilker¹^b
Anterior cingulate cortex	↑Stefurak¹^b; ↑Hilker¹^b
Dorsal anterior cingulate cortex	↓Stefurak¹^b
Frontal cortex	↑Stefurak
Medial frontal cortex	↓Stefurak¹^b
Medial superior frontal	↑Stefurak¹^b
Orbitofrontal cortex	↑Hilker¹^b
Parietal Inferior lobule	↑Hilker¹^b
Frontal motor cortex	↑Stefurak¹^b
Premotor cortex	↑Stefurak¹^b
Primary motor cortex	↑Stefurak¹^b
Medial supplementary motor area	↓Stefurak¹^b
Ipsilateral parietal lobe	↓Stefurak¹^b
Insula	↑Stefurak¹^b
Superior temporal gyrus	↑Stefurak¹^b
Middle temporal gyrus	↓Hilker¹^b
Inferior temporal gyrus	↑Stefurak¹^b
Striatum
Caudate	↓Stefurak¹^b
Putamen	↑Stefurak¹^b
Lentiform nucleus	↑Hilker¹^b
Thalamus
Ventrolateral thalamus	↑Stefurak; ↑Hilker¹^a
Ventroanterior thalamus	↑Stefurak¹^b
Dorsomedial nuclei of Thalamus	↑Stefurak¹^b
Pons	↑Stefurak¹^b
Midbrain	↑Stefurak¹^b
Cerebellum	↑Stefurak¹^b
Right Cerebellar posterior lobe	↑Hilker¹^a
Left Cerebellar posterior lobe	↓Hilker¹^b
Parahippocampal cortex	↑Stefurak¹^b
Occipital lobe	↓Stefurak¹^b

¹Statistically significant,

^bP < 0.001,

^aP = 0.002 vs scans. STN: Subthalamic nucleus; DBS: Deep brain stimulation.

Citation: Williams NR, Taylor JJ, Lamb K, Hanlon CA, Short EB, George MS. Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders. World J Radiol 2014; 6(10): 756-778
URL: https://www.wjgnet.com/1949-8470/full/v6/i10/756.htm
DOI: https://dx.doi.org/10.4329/wjr.v6.i10.756